Significant, named bosses that you have to fight against at some stage of the game. These opponents are the source of Plague Ichor, which is needed in the quest "Spilled Blood".
Boss Fights
Locations on Isola Sacra
1
Echo Knight
Show the map
2Falstead Darak (First Encounter)
Confronting him is one of the objectives of the "Of Rats and Raiders" quest. He will flee at the end of this fight.
3The Caretaker and Tusk
Show the map
4The Lost Huntress
Related quest: The Weeping Sisters.
5The Riven Twins
Related quest: Servant Of God.
6The Winged Brood / Bile Wretch / Blood Wraith
Related quest: Faith And Flame.
7Warrick the Torn
This opponent will stand in your way when you try to reach the Sacrament settlement.
Locations on The Black Trench
8Falstead Darak (Second Encounter)
Fighting this opponent is one of the objectives of the "Of Rats and Raiders" quest.
